Deal Watch: Akebia Gets Phase II Alopecia Areata Candidate From Cost-Conscious Q32

 
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AstraZeneca quietly acquires Six Peaks, plus deals involving Bayer/Dare, Tempest/Factor, XenoTherapeutics/Repare, DayOne/Mersana and more.

Tessera Will Team With Regeneron On Gene-Writing Therapy For AATD

 
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Tessera, which claims its gene-writing technology offers functionality beyond gene-editing, hopes Regeneron can accelerate development of its preclinical alpha-1 antitrypsin deficiency drug.

J&J And Novartis On 2025’s Biggest M&A Deals And What Can Derail A Buyout

 

Three big pharma business development heads at the recent Jefferies conference discussed their activities in 2025, and offered some advice to potential partners on how to avoid deal talks breaking down.

Lundbeck Concedes Avadel Bidding War, But Remains On The Hunt

 
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Lundbeck does not plan to raise its offer for sleep specialist Avadel, clearing the way for Alkermes to win the two-way bidding war.


Gilead Teams Up With Sweden’s Sprint For Latest Oncology Pact

 
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Deal Snapshot: The US company has entered into another cancer drug transaction and bought Sprint's preclinical TREX1 program in a deal that could be worth around $400m.

Biogen Joins The Macrocycle Melee With Dayra Tie-Up

 

Deal Snapshot: The biotech is joining forces with the Versant Ventures-backed startup, paying $50m upfront to apply its macrocycle peptide platform to immunological diseases.

Jefferies 25: Merck’s Cidara Buyout Could Help Meet Needs Of Increasingly Vaccine-Hesitant US

 

Cidara’s long-acting antibody candidate could help protect millions of immunocompromised patients against flu – and could work around growing vaccine hesitancy in the US.

Hanmi Secures North America Beachhead Via Aptose Acquisition

 
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Hanmi is acquiring the Toronto-based biotech, Aptose, following positive early data of its lead asset tuspetinib in AML. The deal also gives Hanmi a strategic foothold in North America and marks another oncology-focused acquisition by a Korean pharma firm.


Asia Deal Watch: GSK To Collaborate With LTZ On Myeloid Cell Engagers

Plus deals involving Adagene/Third Arc, Celltrion/TRiOar, Celltrion/Kaigene, ImmunoScape/Cue, Laekna/Qilu, Lilly/ABL, Lilly/Sanegene, Sanyou/ZJ Bio-Tech, TransThera/Neurocrine, Qyuns/Roche, Otsuka/4D Molecular, IASO/GC Cell, Chugai/Renalys, Henlius/Forlong and Teijin/Elevara.

Merck KGaA To Use Valo’s AI Tech, Real-World Data In Parkinson’s R&D

 
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Deal Snapshot: Merck KGaA is looking to bolster its neuroscience pipeline with novel drugs for Parkinson’s disease and will team with Valo Health on AI-driven discovery work.

Alkermes Fires Back In Bidding War With Lundbeck Over Avadel

 

The drugmaker increased its offer to $21 per share – equal to Lundbeck’s counteroffer – with the same $1.50 CVR tied to Lumryz’s approval, which Avadel called superior.

Jefferies 25: Pfizer Still Hungry For Anti-Obesity Deals After Metsera

 

Forced to spend more than it wanted on Metsera, Pfizer’s M&A coffers are now depleted but it is still interested in weight loss pills and immunology & inflammation assets.


Jefferies 25: Leo Ready To Leap Into More Deals

 
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CEO Christophe Bourdon tells Scrip that the phone is ringing as the Danish drugmaker aims to become ‘the go-to partner for anything in dermatology.’

Glenmark 3.0 In The Making, Invigorated By IGI-AbbVie Deal

 

Buoyed by the milestone AbbVie deal, Glenmark expects to “pay down” its debt and is also changing certain legacy practices as it seeks to ascend the value chain to become more of a branded company.

JNJ Bids $3bn-Plus To Buy Halda, Lead Prostate Cancer Candidate

 
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Looking to enhance its Erleada-led prostate cancer portfolio, Johnson & Johnson will acquire Halda and its Regulated Induced Proximity TArgeting Chimera technology.

Jefferies 25: Biotech Leaders Bullish As M&A Heats Up

 

A rush of bigger M&A deals is inspiring renewed confidence in the biotech sector, but US companies are facing up to unprecedented competition from China.


Merck Offers $9.2bn To Buy Cidara And Phase III Antiviral Flu Preventative

 
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Merck & Co. is looking to bolster its respiratory portfolio with Cidara’s Phase III antiviral conjugate CD388, previously owned by Janssen. Phase III data are expected in 2027.

Another Bidding War As Lundbeck Swoops In On Alkermes/Avadel Deal

 

The Danish drugmaker is offering more per share in cash and CVRs than Alkermes did in the deal announced in October.

Zydus Gears Up For Specialty Acquisitions, Gets gLynparza And Other Approvals

 
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Zydus looks to fill up its coffers ahead of the next round of acquisitions, likely in the specialty drugs space, while US FDA approvals for generics to Lynparza and Vumerity and its first approvals in China and Canada point to a healthy pipeline

Merck KGaA Looks To Repeat SpringWorks Success

 
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The German group is looking at ‘single digit billion’ opportunities, chief financial officer Helene von Roeder tells Scrip.