Vaccine Manufacturers Prepare To Fight Disinformation With Transparency

 

At J.P. Morgan, GSK, Sanofi and Pfizer said they are prepared to address questions about vaccines under a new US administration, while former FDA commissioner Gottlieb warned of threats to public safety.

Executives On The Move: Five CMOs, 14 CEOs And 23 CFOs Among This Week’s Changes

Latest updates include changes at the top at Neuphoria Therapeutics, plus new CEOs at Cyclacel Pharmaceuticals and Norgine, among others.

Acepodia Plays Dual-Payload Ace To Join Global ADC Race

 

Acepodia’s dual-payload antibody-drug conjugates can link multiple tumor-killing agents without antibody modification. Apart from a GPC3-targeting candidate, the Taiwan-US biotech is also working on a bispecific antibody ADC with two different payloads, its CEO tells Scrip in an interview.


XGene’s Non-Opioid Pain Contender Shows Pre-/Post-Op Promise

 
• By 

XGene's pain candidate has shown positive results in a US bunionectomy trial and the Chinese company is also eyeing chronic and cancer pain indications for its contender, which may provide a competitor to Vertex's suzetrigine.

Venture Fund Aims To Enrich Chugai’s Discovery Engine

 

The head of Chugai's new $200m venture capital fund talks to Scrip about its investment priorities.

Oculis Eyes Opportunities For Third Ophthalmology Candidate

 
• By 

The Swiss-headquartered, NASDAQ-listed group has posted a Phase II win for OCS-05 in acute optic neuritis, which opens up its potential in additional, and much larger, neuro-ophthalmic indications, CEO Riad Sherif tells Scrip.

Merck KGaA’s AI Platform Architect On Redefining The Drug Discovery Process

 

The head of AI and automation in drug discovery at Merck KGaA’s life science business talked to Scrip about the company’s AI-powered platform that leverages a “gold mine” of proprietary R&D data, better in silico predictions and the next frontier of AI.


Novartis Hopes To Broaden SMA Patient Pool After Intrathecal Zolgensma Success

 
• By 

The Swiss giant’s blockbuster gene therapy is currently only administered intravenously into patients with spinal muscular atrophy under two years of age. Its intrathecal candidate, called OAV-101, has just passed a Phase III test which could expand its use in children and young adults.

Executives On The Move: Four CEOs And Nine CFOs Among This Week’s Changes

Recent moves in the industry include C-suite changes at Arcutis Biotherapeutics, Kronos Bio and Akari Therapeutics, plus Amgen gets a new chief scientific officer.

Merck KGaA, Aragen Execs On AI-Led Drug Discovery, Incubator Set-up, US Tariffs And More

 
• By 

Merck’s India head for process solutions and Aragen Bioscience’s CEO talk about an incubator set-up and AI-led drug discovery to enable India’s research ecosystem, US tariffs on China, ADC and GLP-1 development, funding path for Goldman Sachs-investee Aragen and more in this video interview

Zealand CEO On Amylins And Obesity: We’re Not Following Novo, We Have Our Own Narrative

 

Adam Steensberg talked to Scrip about his firm’s vision for obesity treatment, Zealand’s independence from neighbor Novo Nordisk, and the hunt for a partner for its amylin candidate, petrelintide.


How Sanofi Is Shaping Plug-And-Produce Manufacturing

 

Sanofi's EVP, manufacturing and supply, Brendan O’Callaghan, tells Scrip how modular concept manufacturing at a new site in Singapore can drive efficiencies and minimize downtime, with technologies such as digital twins expected to further improve operational metrics.

Why J&J Still Wants In On Atopic Dermatitis

 

The immunology company has used business development to bring in atopic dermatitis bispecific antibodies. J&J VP-immunodermatology disease area leader Liza O’Dowd talked to Scrip about the developments.

Beleaguered BenevolentAI Goes Back To Its Roots

 
• By 

Founder Ken Mulvany has returned to the artificial intelligence drug discovery specialist determined to ensure it plays to its “foundational strengths.” The UK firm has therefore initiated a major restructuring plan, along with the intention to delist from Euronext Amsterdam.

Citryll Hits Back Of the NET With €85m Financing

 
• By 

The Dutch group has assembled an impressive syndicate which is betting that the first-in-class monoclonal antibody CIT-013 could be a transformative treatment for rheumatoid arthritis and hidradenitis suppurativa.


Benzos to Breakthroughs: Bill Burns on Roche’s Transformation

 
• By 

Former Roche CEO Bill Burns reflects on transforming Roche into a global leader in specialty care and oncology. Now, as he spearheads efforts to combat antibiotic resistance, Burns shares insights on industry evolution, the power of cultural change, and the urgent need for a new business model in antibiotics development.

Executives On The Move: 17 New CEOs, Nine CFOs And Four CMOs Among This Week’s Changes

Recent moves in the industry include C-suite changes at Moderna, Valerio Therapeutics and Ocugen, plus IDEAYA Biosciences acquires chief commercial officer from Gilead Sciences.

Industry Successes Shine At The 20th Annual Scrip Awards

 
• By 

The Scrip Awards has been celebrating industry successes for 20 years now and the 2024 ceremony at the beautiful Raffles London at the OWO saw Novo Nordisk and Bill Burns taking home the top prizes.

Health Care Industry Reels After UnitedHealthcare CEO Is Killed Outside NYC Hotel

 
• By 

The motive for the shocking murder of Brian Thompson in New York City was still unknown Wednesday afternoon.