PureTech Weighs Up Pros And Cons Of Going Private

 
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The biotech has rejected a takeover bid from Nordic Capital but a sale to private equity could be a solution to the public market's continued reluctance to adequately value PureTech’s hub-and-spoke business model.

GSK Ramps Up Neuroscience Investment With ABL Brain Shuttle Deal

 

The pact could be worth more than $2.6bn and adds to growing big pharma investment in the technology.

Epsilogen Hits Antibody Acquisition Trail With TigaTx Takeover

 
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Following the near-total dominance of IgG antibodies, the UK group is backing the potential of IgA and IgE-based therapies to transform cancer treatment with the purchase of US-headquartered TigaTx.

Novo Adds Lexicon’s Novel Obesity Drug To Deal Flurry

 

The obesity market leader has unveiled its second deal in days, paying $75m upfront for a potential first-in-class ACSL5 inhibitor, while the deal also provides some respite for Lexicon.


Major Cash Injection Advances Augustine’s HDAC6 Hopes

 
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The Belgian firm banks nearly €77.7m to push its Charcot-Marie-Tooth to proof-of-concept.

Roche Adds To Its Antibody Armoury With OBT Alliance

 
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Deal Snapshot: The antibody-drug conjugate field continues one of the hottest dealmaking spaces and Roche continues to invest heavily. Its latest pact could be transformative for the UK firm which already has a decent number of big pharma partners.

New Duchenne Results Put Avidity On Course For Filing

 

The potential first-in-class antibody oligonucleotide conjugate could treat a form of the muscle wasting disease, and could be the first of Avidity’s trio of rare disease drugs to gain approval.

Big Pharma Backing For Sofinnova Biotech Acceleration Plans In Europe

 
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The Biovelocita II fund is supported by the likes of Amgen, Bristol Myers Squibb and Pfizer


Zealand Turnaround Complete In Three Years

 
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CEO Adam Steensberg has led a major change in fortunes for the Danish biotech since March 2022.

Callio Therapeutics Aims To Overcome Enhertu Resistance With Multi-Payload ADCs

 

The Singapore and Seattle-based biotech is joining the race to bring a ‘double whammy’ antibody-drug conjugate to patients.

What’s Hot And What’s Not For Sofinnova

 
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Chairman Antoine Papiernik spoke to Scrip about the therapeutic areas that where the VC major is looking at to invest its considerable cash pile.

Is Mittelstand The Missing Piece In India’s Q Quotient?

 
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Can India’s Mittelstand or small and medium enterprises win the quality game and what could help? Sectoral insights from defense and FMCG industries and from other countries like Germany might hold the key for Indian pharma, a panel of experts at a recent event opined.


Sofinnova Raises €1.2bn To Find Biotech’s ‘Diamonds in The Rough’

 
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Although it was no walk in the park, Europe’s leading life sciences VC firm has amassed a huge pot of cash for biotechs and will use its AI capabilities to find up to 60 start-ups to support.

Japan-Korea Venture Collab Grows With VC And Regulatory Meetups

 
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Cross-Asian initiative has already brought several South Korean gene and cell therapy startups and Japanese VCs closer, with further hopes for product development and launches in Japan, regulatory harmonization and gliobalization.

Verve Can Shrug Off Vertex Loss But Lilly Opt-In Is Crucial

 

The company will soon have Phase I data on its in vivo gene-editing PSCK9 inhibitor and hopes Lilly is persuaded to opt into its development.

Korea Biotech Roundup: Orum, DongKook Price IPOs Below Band

 
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The latest activity in the South Korean biotech sector includes IPOs by Orum and Dongkook Life, as well as progress with ADCs at multiple firms.


European Oncology Biotechs Start Ominous ‘Strategic Reviews’ To Survive

 
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Norwegian firm BerGenBio, Lava of the Netherlands and Poland’s Ryvu are all weighing up diverse options to maximize shareholder value and stay alive, including licensing agreements and mergers.

Immusoft Goes For Cell Therapy Plan ‘B’

 

Emerging Company Profile: CEO Sean Ainsworth spoke with Scrip about how the company is developing B-cell therapies to treat a range of diseases, starting with MPS I.

Hookipa Pulls Out Of Poolbeg Deal

 

The Anglo-Irish biotech has been left surprised by Hookipa’s change of heart after it agreed a sale to create a US-listed entity as the year began.

Ascletis Becomes Another Contender For ‘Best-In-Class’ Oral GLP-1

 

ASC30's Phase I study has produced the best-yet weight loss achieved by an oral drug at 28 days, and it could be a serious rival for Lilly’s frontrunner orforglipron.