Interviews

Novartis Development Head On The India Hub, AI And Not Doing ‘Me Too’ Stuff In Obesity

 

Novartis president, development and chief medical officer talks about the pivotal role of the development India hub in progressing breakthrough drugs, how AI is delivering gains in the trials arena, driving focus in the R&D engine and the Swiss group’s approach in the obesity space.

Parexel Leaders On Trial Diversity, AI And What’s Holding Sponsors Back In India

 

Parexel's CEO Peyton Howell and India boss Sanjay Vyas talk to Scrip about the value of clinical trial diversity, AI pilots underway and opportunities for India amid geopolitical rumblings, as well as the need for standardized regulatory approaches to enhance sponsor interest.

Lexicon Has A Lot Riding On LX9211 Phase IIb Readout In Pain

 

CEO Mike Exton talked to Scrip about moving the company forward after a disappointingly disruptive 2024.

Bridge Biotherapeutics Confident In IPF Contender As It Seeks Global Partner

 
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The CEO of Korean biotech Bridge Biotherapeutics shares progress and strategy for its lead candidate for IPF, along with thoughts on what Trump and the ongoing Korean political crisis might mean for the industry.


How Research Head Jane Grogan Is Reinforcing Biogen’s Internal And External R&D Focus

 
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CEO Christopher Viehbacher has said repeatedly that Biogen will build its pipeline internally and through deals, and Grogan reshuffled the research organization with that in mind.

BMS Enters A Catalyst-Rich Era Full Of Both LOEs And New Launches

 
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Bristol Myers Squibb has been in a rapid growth phase to make up for upcoming losses of exclusivity. Scrip spoke with executives about further catalysts coming in the next 18-24 months.

Lilly CMO David Hyman On The Company’s Drive To Take ‘Ambitious Swings’ In R&D

 
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Lilly’s revenue is rising rapidly based on its successes in diabetes and obesity, and the company is reinvesting in big plays in those markets as well as in cancer, lipid-lowering and other indications.

Novartis’s Bulto: Kisqali Is Blueprint For More Competitive US Launches

 

Novartis enjoyed exceptional growth in 2024, and its US leader, Victor Bulto, puts that down to greater R&D and commercial co-ordination paying off with drugs such as Kisqali in early breast cancer.


Enhertu, Datroway Approvals Start Off A Big Year For Daiichi

 

The year is off to a good start for the Japanese pharma with back-to-back approvals in the US. CEO Ken Keller talked to Scrip about some recent setbacks and looking ahead.

Acadia’s New CEO Outlines Growth Strategy

 

Continuing to grow Nuplazid and Daybue are top priorities along with pipeline and business development, Catherine Owen Adams told Scrip.

R&D In The IRA Era: Takeda Opts Not To Develop Zasocitinib For Lupus

 

The TYK2 inhibitor is in Phase III development for plaque psoriasis and psoriatic arthritis but the company said it will not pursue late-stage studies in lupus, partly due to the Inflation Reduction Act.

Servier Plots Route Into Neurology Through BD

 

CEO David Lee, who oversees Servier’s US business, and chief scientific officer Claude Bertrand talked to Scrip at J.P. Morgan about expanding into neurology through business development.


Sabry Lays Out BioMarin’s New Business Development Plan

 

BioMarin chief business officer James Sabry recently joined the company from Roche and talked to Scrip about plans to jumpstart BD at the smaller company.

Sangamo Nearing Fabry Gene Therapy Deal To Fund Its Pipeline

 
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Low on cash when Pfizer handed back rights to its hemophilia A gene therapy, Sangamo is talking to partners for its Fabry disease gene therapy to fund its two lead programs through proof-of-concept.

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Acepodia Plays Dual-Payload Ace To Join Global ADC Race

 

Acepodia’s dual-payload antibody-drug conjugates can link multiple tumor-killing agents without antibody modification. Apart from a GPC3-targeting candidate, the Taiwan-US biotech is also working on a bispecific antibody ADC with two different payloads, its CEO tells Scrip in an interview.


XGene’s Non-Opioid Pain Contender Shows Pre-/Post-Op Promise

 
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XGene's pain candidate has shown positive results in a US bunionectomy trial and the Chinese company is also eyeing chronic and cancer pain indications for its contender, which may provide a competitor to Vertex's suzetrigine.

GSK-Backed Ouro Launches With $120m For T-Cell Engagers In Autoimmune Diseases

 
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Ouro Medicines, founded by Monograph Capital and GSK and helmed by HI-Bio veterans, aims to reset the immune system in B-cell-mediated diseases with options that are not CAR-T therapies.

Venture Fund Aims To Enrich Chugai’s Discovery Engine

 

The head of Chugai's new $200m venture capital fund talks to Scrip about its investment priorities.

Oculis Eyes Opportunities For Third Ophthalmology Candidate

 
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The Swiss-headquartered, NASDAQ-listed group has posted a Phase II win for OCS-05 in acute optic neuritis, which opens up its potential in additional, and much larger, neuro-ophthalmic indications, CEO Riad Sherif tells Scrip.