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Exelixis Hopes CABOSUN Means New Dawn For Cabometyx In Frontline Kidney Cancer

 
• By Emily Hayes

Exelixis’s plan to file an sNDA, based on positive results in the Phase II CABOSUN study, could support an early approval for cabozantinib in first-line kidney cancer, spuring more change in the crowded kidney cancer market

Exelixis Inc.'s cabozantinib is poised to move into frontline treatment of renal cell carcinoma, possibly spurring another change in the standard of care for the disease, following a positive release of results in the Phase II CABOSUN head-to-head study against Pfizer Inc.'s Sutent.

Cabozantinib is currently marketed as Cometriq for metastatic medullary thyroid cancer and is marketed and as Cabometyx for renal cell carcinoma after prior antiangiogenic therapy

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