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Regulus RNAi Candidate Can Reduce HCV Treatment To Four Weeks

 
• By Joseph Haas

Although it is on FDA clinical hold to resolve safety concerns about jaundice, RG-101 has shown the ability to significantly reduce the length – and perhaps cost – of HCV therapy when combined with current direct-acting antivirals.

BOSTON – New data on Regulus Therapeutics Inc.’s RNA interference drug RG-101, which had been submitted for presentation at the American Association for the Study of Liver Diseases meeting, show that the Phase II candidate has the efficacy to help it find a commercially viable route into the hepatitis C market, if the company can get past a clinical hold placed by FDA earlier this year.

The Phase II data showing that RG-101 in combination with direct-acting antiviral (DAA) therapy can reduce duration of treatment for hepatitis C to four weeks, was released ahead of the...

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More from Anti-infective

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• By Joseph Haas

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Gilead Ready To Go After Hepatitis D Again

 
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Chinese Vaccine Makers Turn To Emerging Markets

 
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More from Therapy Areas

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• By Sushmita Panda

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Astellas Gets CLDN.18.2-Targeted ADC From China’s Evopoint

 
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Merck & Co./Daiichi Pull Patritumab Deruxtecan BLA On Disappointing OS

 
• By Jessica Merrill

Patritumab deruxtecan is the lead antibody drug conjugate in a $22bn deal signed between the two partners, with the decision marking a disappointing setback