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Ibrance Trial Cements CDK4/6 Inhibitors As Standard Of Care In Breast Cancer

 
• By Emily Hayes

New England Journal of Medicine editorial sings the praises of CDK4/6 inhibitors in breast cancer, which include Pfizer's Ibrance, Novartis's ribociclib and Elli Lilly's abemaciclib.

Full results for Pfizer Inc.'s cyclin-dependent kinase 4/6 inhibitor Ibrance in the confirmatory PALOMA-2 study cement the position of the class in the first-line treatment of hormone receptor-positive, human epidermal growth factor receptor-2 negative (HR+/HER2-) breast cancer, with potential to move to the adjuvant and neoadjuvant settings.

Data for Ibrance (palbociclib) in the first-line PALOMA-2 study were published in the New England Journal of Medicine on Nov. 17 by UCLA's Richard Finn and colleagues, following up on a presentation at the American Society of Clinical Oncology meeting in June

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