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MiNA Pursuing The Other Side Of RNA Interference With Small Activating RNA Approach

 
• By Joseph Haas

London biotech seeks to up-regulate CEBP alpha gene in the liver to provide a therapeutic option for patients with both cirrhosis and hepatocellular carcinoma. MiNA’s first candidate is in Phase I and should move into a pair of Phase II trials in 2017.

London biotech MiNA Therapeutics is aiming high with its novel small activating RNA (saRNA) therapeutics, going after the toughest possible patient base in liver disease because, as CEO Robert Habib put it, soaring ambition should be the very purpose of novel technology – to produce transformational results.

The privately backed start-up is hoping to offer a therapeutic option for the sickest liver disease patients with a novel technology that has the reverse effect of RNA interference: its small activating RNA (saRNA) therapeutics in theory will

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