Seattle Genetics/BMS Blood Cancer Tie-Up May Expand After Good Combo Data

Combo of Seattle Genetics' antibody-drug conjugate Adcetris and BMS's PD-1 inhibitor Opdivo demonstrates 90% objective response rate and 62% complete response rate in relapsed Hodgkin lymphoma, and further investigation of the pairing seems on the cards.

Seattle Genetics Inc. CEO Clay Siegall envisions a broader collaboration with Bristol-Myers Squibb Co. on blood cancer combinations following the release of encouraging data for the anti-CD30 antibody-drug conjugate Adcetris and the PD-1 inhibitor Opdivo in relapsed Hodgkin lymphoma.

Adcetris (brentuximab vedotin), which is partnered with Takeda Pharmaceutical Co. Ltd., is approved for classical Hodgkin lymphoma after the failure of autologous hematopoietic stem cell transplantation (HSCT) and also...

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