AML Pipeline Update: Pharmas Pursue Big Breakthroughs In Niche Spaces

Unmet need in acute myeloid leukemia is very high, but that doesn't mean standards will be low for the many companies pursuing therapies in the space.

 Leukemia cell (blast cell)

The acute myeloid leukemia field looks set for a shakeup with the potential US market entry of Novartis AG's midostaurin, several other candidates in Phase III, and a new master trial aimed at rapid development of targeted drugs.

Progress in AML has been slow – the five-year survival rate is only 26% – and the standard of care has been the same for decades

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