It looks as though Pfizer Inc. might have to offer a discount or some other type of patient access scheme if it wants to secure a positive recommendation from NICE, the HTA for England and Wales for its breast cancer drug Ibrance (palbociclib). NICE has issued preliminary recommendations declining to recommend the drug for hormone receptor-positive (HR+)/human epidermal growth factor receptor 2-negative (HER2-) breast cancer. It says the benefits of the drug, widely expected to become a standard of care, do not justify its costs.
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