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Pfizer To Compromise On NICE Price For Ibrance?

 
• By Francesca Bruce

NICE, the HTA for England and Wales, is poised to say no to Pfizer’s Ibrance (palbociclib), because the cost of the drug is too big in relation to its benefits. The company will likely have to come back with a patient access scheme to secure reimbursement.

Money Wave

It looks as though Pfizer Inc. might have to offer a discount or some other type of patient access scheme if it wants to secure a positive recommendation from NICE, the HTA for England and Wales for its breast cancer drug Ibrance (palbociclib). NICE has issued preliminary recommendations declining to recommend the drug for hormone receptor-positive (HR+)/human epidermal growth factor receptor 2-negative (HER2-) breast cancer. It says the benefits of the drug, widely expected to become a standard of care, do not justify its costs.

On 3 February NICE published draft guidance rejecting Ibrance in combination with an aromatase inhibitor for previously untreated metastatic, hormone receptor-positive, HER2-negative breast cancer. The initial recommendations are not a...

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