Tetraphase Bets On I.V. Eravacycline Rerun As Antibiotic Market Influx Looms

Tetraphase has been keeping its head down since a 2015 Phase III trial failure for its lead antibiotic drug eravacycline sliced around $1.3bn from the company's market cap – but 2017 will be a turnaround year, says CEO Guy Macdonald.

Guy Macdonald
Tetraphase CEO Guy Macdonald Has High Hopes For Lead Antibiotic Despite Past Failure • Source: Tetraphase Pharmaceuticals

After a disappointing late-stage setback for its lead antibiotic compound in September 2015, publicly traded Tetraphase Pharmaceuticals Inc. is back on track to get its first drug filed by the end of this year, CEO Guy Macdonald told Scrip in a recent interview.

"2016 was our year of getting things done after a setback the previous year," Macdonald said. He highlighted that the company is expecting Phase III data in the third quarter for its lead compound, eravacycline, as an intravenous (I.V.) treatment for complicated intra-abdominal infections

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