1. Scrip
  2. >>Therapy Areas
  3. >>Anticancer

Merck's Keytruda Offers Hope And Risk In Early Breast Cancer

 
• By Emily Hayes

I-SPY2 study shows promising efficacy for PD-1 inhibitor Keytruda in combination with chemo in high-risk breast cancer – including a tripling of response rate in triple-negative breast cancer – but also raises red flag on immune-mediated adverse events in early-stage patients.

Conference

Merck & Co. Inc.'s anti-PD-1 Keytruda has strong potential in combination with paclitaxel chemotherapy in very early treatment of HER2-negative breast cancer, according to new data, but risks are also emerging in this setting and could have implications for other drugs in the class.

Keytruda (pembrolizumab) is currently approved for lung cancer, melanoma, classical Hodgkin lymphoma, head and neck squamous cell cancer, bladder cancer...

Read the full article – start your free trial today!

Join thousands of industry professionals who rely on Scrip for daily insights

  • Start your 7-day free trial
  • Explore trusted news, analysis, and insights
  • Access comprehensive global coverage
  • Enjoy instant access – no credit card required
Start Free Trial

Already a subscriber?

More from Anticancer

More from Therapy Areas

Scholar Rock Shows Muscle-Building PoC In Obesity

 
• By Jessica Merrill

The company said it intends to maintain a focus on rare neuromuscular disease with apitegromab but could consider partnering in obesity.

Spyre Takes Aim At Roche And J&J In Inflammatory Diseases

 
• By Andrew McConaghie

The US firm was already looking to compete in ulcerative colitis, but now expands its ambitions by moving into rheumatoid arthritis as well.

Draig Is All Fired Up To Transform Neuropsychiatric Field

 
• By Kevin Grogan

Wales-based group launches with $140m series A.