Corvus Aims To Master Adenosine Mechanisms For PD-1/L1 Failures

Emerging Company Profile: CEO Richard Miller, who co-founded Idec and Pharmacyclics, explains Corvus's approach of building a pipeline around an emerging target in cancer immunity that may be complementary to checkpoint inhibitors and other therapies.

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Corvus Pharmaceuticals CEO Richard Miller

Corvus Pharmaceuticals Inc. hopes to catch the next wave of the immuno-oncology revolution by developing drugs that can treat patients who are resistant/refractory to PD-1/L1 inhibitors, by blocking the effects of the signaling molecule adenosine.

It's impossible to overestimate the impact that checkpoint inhibitors have had in cancer treatment. In some tumor types, however, response...

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