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Bristol's Opdivo/Yervoy Combo Beats Sutent On Survival In Renal Cancer

 
• By Jessica Merrill

The combination of Opdivo and Yervoy showed a survival advantage in renal cancer in a Phase III trial, adding to the understanding that overall survival may be a better endpoint than progression-free survival for measuring immuno-oncology drugs.

Digital illustration of Cancer cell in colour background

Immuno-oncology combinations have faced disappointing clinical trial data of late, but positive news from Bristol-Myers Squibb Co.'s Phase III trial testing its PD-1 inhibitor Opdivo (nivolumab) and CTLA-4 inhibitor Yervoy (ipilimumab) in advanced renal cell cancer could swing the pendulum back in their favor.

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