Bayer's Aliqopa Approval Gives PI3K Class A Second Chance in Follicular Lymphoma

Bayer's PI3 kinase inhibitor copanlisib now has accelerated approval in a common type of non-Hodgkin lymphoma, but the drug's competitive profile still awaits Phase III data.

White blood cells in peripheral blood smear, Wright stain

The class of PI3 kinase inhibitors will get a second shot at penetrating the market for follicular lymphoma, following accelerated approval of Bayer AG's Aliqopa (copanlisib) for use as a monotherapy after two prior systemic therapies, but the drug will need to prove it is safe and efficacious in combination regimens in Phase III to come into wider use.

The drug cleared the US FDA Sept. 14, and Bayer is planning to launch the drug immediately at the monthly wholesale acquisition cost of $12,600

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