Finance Watch: Genocea, Mateon Shift Strategies, Cut Jobs To Preserve Cash

Genocea shifts to preclinical neoantigen-based cancer vaccines rather than advance a Phase III-ready herpes program on its own and Mateon gives up on its lead drug as placebo outperforms. Also, Juno tops recent public company financings and new VC funds back early-stage firms.

Finance Watch

Investors apparently aren't as enthusiastic about Genocea Biosciences Inc.'s neoantigen-focused cancer vaccine program as its CEO is, because the company's stock plunged after it revealed plans to shelve a Phase III-ready herpes therapy to focus on the preclinical immuno-oncology platform.

Genocea made the strategic shift despite the positive Phase IIb results for GEN-003, an immunotherapy for the treatment of genital herpes, that it reported in July. (Also see "Pipeline Watch: Phase III Starts With Rimegepant, ARQ087 And SGX942" - Scrip, 31 July, 2017.) Meanwhile, Mateon Therapeutics Inc

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