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More Vaccine Disappointment For Sanofi As First C Diff Toxoid Vaccine Fails

 
• By Alexandra Shimmings

A second dose of bad news for Sanofi's vaccines unit sees its C. difficile vaccine dropped after a Phase III study was deemed unlikely to succeed.

Clostridium difficile bacteria
Clostridium Difficile A Tough Target • Source: Shutterstock

The failure ofSanofi's investigational vaccine against Clostridium difficile after a planned interim analysis of a Phase III study showed it was unlikely to meet its primary endpoint raises some questions over the therapeutic approach of targeting a vaccine against C diff toxins, and will delay development of one of its rivals.

The interim analysis and decision to terminate development also comes just days after new data reduced the commercial potential of...

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In Brief: Gilead HIV Trials On Hold Over Safety Signal

 
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With ACIP Upheaval, Merck & Co. Among Those Left In A Lurch

 
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• By Joseph Haas

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