Following the sale of Actelion Pharmaceuticals Ltd. for $30bn to Johnson & Johnson in the summer, the new venture set up by the former's founder Jean-Paul Clozel - Idorsia Pharmaceuticals Ltd. - is banking another $230m from the healthcare giant after signing a deal for the investigational hypertension drug aprocitentan.
Clozel drove a hard bargain when negotiating the sale of Actelion and managed to get an extra $1bn out of J&J to set up Idorsia, where he is CEO, with the earlier-stage assets left over from the acquisition. One of them was aprocitentan, previously known as ACT-132577, an orally active dual endothelin receptor antagonist (ERA)