What's New And What's Next In CAR-T After ASH

Incremental updates at the recent ASH meeting shed light on which products may follow Novartis' Kymriah and Gilead/Kite's Yescarta into the commercial market. Will it be Celgene and Bluebird or Celgene and Juno? Where do Pfizer, Servier and Cellectis stand with their off-the-shelf options?

Destruction of leukaemia cell, conceptual image. 3D illustration which can be used to illustrate blood cancer treatment

Novartis AG and Gilead Sciences Inc.'s recently acquired subsidiary Kite Pharma Inc. have the only two approved chimeric antigen receptor T cell (CAR-T) therapies, but bluebird bio Inc. and its partner Celgene Corp. were the stars of the recent American Society of Hematology (ASH) annual meeting.

Both Novartis' Kymriah (tisagenlecleucel) and Gilead/Kite's Yescarta (axicabtagene ciloleucel) are comprised of patients' own T cells reengineered to target cancer...

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