Heart Failure Pipeline Review: Amgen's Omecamtiv And Merck's Vericiguat Step Up To Plate

In addition to small molecules, stem cell therapies promise to help rejuvenate the chronic heart failure pipeline, but high prices and invasive procedures may limit their use to end-stage patients, and skepticism about efficacy persists.

3d rendering Human Heart

Merck & Co. Inc./Bayer AG's soluble guanylate cyclase stimulator vericiguat and Amgen Inc.'s novel inotropic molecule omecamtiv mecarbil, both in Phase III, are each projected to bring in over $1bn in chronic heart failure drug sales in major markets in 2026, accounting for more than one-fifth of total revenue for that year, according to a new pipeline review from Datamonitor Healthcare.

The chronic heart failure (CHF) market is dominated by generics; angiotensin receptor blockers (ARBs) and angiotensin converting

Read the full article – start your free trial today!

Join thousands of industry professionals who rely on Scrip for daily insights

  • Start your 7-day free trial
  • Explore trusted news, analysis, and insights
  • Access comprehensive global coverage
  • Enjoy instant access – no credit card required

More from Cardiovascular

More from Therapy Areas