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Scrip's Rough Guide To IL-2: Mother Of All Cytokines

 
• By Emily Hayes

Nektar Therapeutics, Alkermes and Roche are among the companies with new solutions for more safely targeting an old cytokine well validated in cancer immunotherapy. Top execs explain how and why.

LI-2 Protein_564977620_1200.jpg
Interleukin-2 is a small protein that stimulates cell signaling in the immune system

Interleukin-2 traditionally has been associated with nasty toxicities like the potentially fatal, flu-like cytokine release syndrome, but these days – with Nektar Therapeutics' NKTR-214 up on a pedestal – it's drawing feverish interest from investors.

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• By Sushmita Panda

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• By Kevin Grogan

The Oxford group has linked up with the NHS Cancer Vaccine Launch Pad.

Bristol’s Opdivo + Yervoy Gets FDA Liver, Colorectal Cancer Nods

 
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Novartis $23bn US Investment Is Music To Trump’s Ears

 
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The Swiss major follows Lilly and J&J in committing to a significant spend on US manufacturing.