Sophiris Targets Prostate Cancer With Modified Biologic

Nearly 140,000 men each year are diagnosed with localized prostate cancer, and the common treatment is radical - surgical removal of the prostate or whole organ radiation. Sophiris Bio is a San Diego-based biotech developing topsalysin for the focal treatment of localized prostate cancer, and may spare the organ from such massive collateral damage. Speaking at the Biotech Showcase, Sophiris CEO Randall Woods explained to Scrip how topsalysin works and how he is looking to continue clinical development of the biologic, in both localized prostate cancer and benign prostatic hyperplasia.

Video interview

C#200400833:Sophiris Bio Inc.] is expecting 2018 to be a pivotal year for the company. It aims to unveil data relating to a Phase IIb trial of topsalysin in localized prostate cancer, complete preparation for a single Phase III registration trial for the indication, as well as look for support to develop the biologic as a treatment for benign prostatic hyperplasia, which has completed one Phase III trial.

While the company has funds to complete the Phase II trial it is looking for additional funds and partners to pursue a single Phase III registration trial in localized prostate...

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