Arena Ready For Etrasimod Phase III Face-Off With Celgene's Ozanimod In UC

With significant Phase II results in ulcerative colitis, Arena is planning a Phase III program for its selective S1P receptor modulator etrasimod – a drug that it thinks can best Celgene's S1P-targeting therapy ozanimod on safety and possibly efficacy.

3d render illustration of human digestive system - front view

Arena Pharmaceuticals Inc.'s S1P receptor modulator etrasimod is ready to move into Phase III after the company reported much-anticipated positive results from the Phase II OASIS clinical trial in ulcerative colitis – an indication where Celgene Corp.'s competing drug ozanimod already is in Phase III.

San Diego-based Arena, continuing to advance its in-house programs after giving up hope of commercial success for obesity drug Belviq (lorcaserin), believes that its selective S1P modulator has

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