Interview: CellCentric Prostate Cancer Drug Promises Much

The Cambridge-based company's CEO Will West tells Scrip that CCS1477 has shown a lot of potential for patients with late-stage prostate cancer who are resistant to second-line anti-androgen drugs like Zytiga and Xtandi and the $26m it has just raised will help fund development of the epigenetic therapy up to Phase IIb.

Prostate cancer
CellCentric says it has a first-in-class prostate cancer therapy • Source: Shutterstock

Having investigated around 60 potential epigenetic-related drug targets, the UK's CellCentric Ltd. believes it has found one that is a first-in-class candidate for treatment-resistant prostate cancer and is heading to the clinic with $26m in new funds.

The Cambridge-headquartered privately held biotech has raised all the cash from one of its existing backers - Morningside Venture Investments – to finance clinical testing of CCS1477, an inhibitor of the twin histone acetyl transferase proteins p300 and CBP

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