Finance Watch: Regulus Shrinks To Preserve Cash, Ironwood Cuts Jobs Ahead Of Split

Public Company Edition: Long-struggling Regulus is laying off employees and pausing its two clinical programs. Also, Ironwood is shuffling staff ahead of splitting into two companies and will cut 40 jobs in the process. And among several loan agreements and note sales, Tesaro borrows another $200m.

Finance Watch

Regulus Therapeutics Inc., which has been struggling for years, said on July 6 that it is cutting its head count by 60%, halting enrollment in its two clinical programs, and reprioritizing its preclinical research and development. The announcement sent its stock down 52.1% to $0.35.

San Diego-based Regulus, which develops drugs targeting microRNAs, said that it will focus preclinical R&D on its hepatitis B research and seek partners for all other preclinical programs, including glioblastoma multiforme, non-alcoholic steatohepatitis (NASH) and immunology

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