Chugai May Not Win Race For $500m Neuromyelitis Optica Market, But May Best Soliris On Ease Of Use

While Chugai’s satralizumab may not be odds on to win the race for approval, it may beat Alexion’s Soliris on ease of use with a regimen of subcutaneous application once a month versus Soliris’ fortnightly IV.

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A Phase III study of Chugai Pharmaceutical Co. Ltd. ’s anti-IL-6 receptor monoclonal antibody (MAb) satralizumab for neuromyelitis optica spectrum disorder (NMOSD) has shown to, on top of immunosuppressive therapy, significantly reduce the risk of relapse by 62%, and by 79% in AQP4-positive patients. The MAb also demonstrated a good safety profile. T 

There are no current approved therapies for NMOSD, which is an inflammatory disease of the central nervous system in which there are episodes of inflammation and damage to the myelin that almost exclusively affect the optic nerves and spinal cord

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