Cyclenium Pharma Inc., founded five years ago by Helmut Thomas and Mark Petersen in Quebec, Canada, is a small molecule macrocycle company with a drug discovery technology, Customized Macrocycles for Recognition of Topologies (CMRT), and a screening library, QUEST, for the discovery and development of drugs for areas of unmet medical need.
Macrocyclic drug discovery fills the molecular space between traditional small molecules and large bio-molecules. Although Cyclenium Pharma has been incorporated for just five years, its founders and team came from...
Tranzyme was one of the pioneers in the generation and use of small molecule macrocycles for drug discovery. Having lost the patents to previous work, Thomas, previously senior vice president...
