AbbVie Inc. and Roche have announced their first-in-class BCL-2 inhibitor, venetoclax (Venclexta in the US, Venclyxto in Europe) has met the primary endpoint in a German clinical study which could allow the drug's indications to be extended to the first-line treatment of chronic lymphocytic leukemia (CLL), a therapeutic sector shaping up to become notably competitive.
The use of a combination of venetoclax and Roche/Biogen Inc.'s anti-CD20 MAb, Gazyva (obinutuzumab) for a fixed duration of...