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NextCure Hopes Its Novel Target Therapies Will Treat Patients Not Helped By PD-1/L1 Inhibition

 
• By Joseph Haas

Emerging Company Profile: Based on discovery research at Yale, NextCure hopes S15 and other novel targets will provide new inroads in immuno-oncology, while much of the field remains focused on PD-1 inhibitors and combinations.

Emerging Company Profile Regular column feature image Version 2

Business is booming for NextCure Inc., which took its first novel targeted immuno-oncology candidate into clinical development after raising a $93m Series B financing and finalizing a research collaboration with Eli Lilly & Co. that it says will feed both companies’ R&D pipelines.

All of that occurred within the past few months for the Beltsville, Md.-based firm founded on research from the Yale University lab of Lieping Chen, NextCure’s founder. The start-up launched in 2015 and raised a $67m Series A round the following year backed by Canaan Partners, Lilly Asia Ventures, OrbiMed Advisors, Pfizer Inc. and Sofinnova Ventures

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