After Imbruvica Passes Chemo-Free Tests, Shorter Duration Regimens Could Be Next Value-Adds

AbbVie/Pharmacyclics executives Danelle James and Mohamed Zaki, in an interview at ASH, discussed Imbruvica's worth in chemo-free settings and noted additional value that could be created with shorter durations of treatment in combination regimens.

 Ladder made of coins with colorful pills on top suggesting the growing prices of medicine or drugs

AbbVie Inc.'s Imbruvica (ibrutinib) made a big splash at the American Society of Hematology (ASH) meeting earlier this month with multiple studies making the case for the Bruton's tyrosine kinase (BTK) inhibitor as a new chemotherapy-free standard of care in chronic lymphocytic leukemia (CLL). But the company and its partner – Johnson & Johnson's Janssen Pharmaceutical Cos. – continue to look for additional value that the drug can bring to patients, physicians and the health care system.

Imbruvica was added to AbbVie's portfolio with the $21bn acquisition of Pharmacyclics Inc. in 2015. (Also see "AbbVie outdoes rumored J&J bid with $21bn Pharmacyclics buy" - Scrip, 5 March, 2015

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