GlaxoSmithKline PLC's return to the oncology space has been confirmed by the UK major making a hefty €300m upfront payment to get access to Merck KGAA's bifunctional immunotherapy M7824 (bintrafusp alfa).
M7824 has been designed to simultaneously target two immuno-suppressive pathways - transforming growth factor-β (TGF-β) trap and an anti-programmed cell death ligand-1 (PD-L1)
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