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Questions Persist On Lilly’s Tirzepatide And Tolerability

 
• By Jo Shorthouse

Concerns about gastrointestinal tolerability continue to weigh on Lilly’s tirzepatide, despite improvements seen in a Phase II dose-escalation study. Lilly believes the adverse events are manageable. 

Sugar castle
• Source: Shutterstock

Eli Lilly & Co. investors have been eagerly awaiting more details on the investigational dual GIP and GLP-1 receptor agonist tirzepatide for type 2 diabetes, but while new Phase II data presented at the American Diabetes Association Scientific Sessions, showed an improvement, it did not alleviate concerns about tolerability. 

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