GSK's Zejula Poised To Take On Lynparza In First-Line Ovarian Cancer

The Phase III PRIMA study in first-line ovarian cancer was positive for progression-free survival in patients regardless of their biomarker status, GSK reported.

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GlaxoSmithKline PLC's poly ADP-ribose polymerase (PARP) inhibitor Zejula (niraparib) could have an edge over rivals as a first-line maintenance therapy in ovarian cancer based on results from the positive Phase III PRIMA trial in the broad population.

The double-blind, placebo-controlled study met its primary endpoint of a statistically significant improvement in progression free survival for women regardless...