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Novartis Snaps Up KRAS Inhibitor R&D

Difficult-To-Target Oncogenic Proteins Yield To Drug Discovery

 
• By John Davis

Novartis has taken an option on novel inhibitors of the KRAS cell signaling pathway while it funds the drug discovery research at the Cancer Research UK’s Beatson Institute.    

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Signaling pathways are disrupted in many cancers. • Source: Shutterstock

Novartis AG is the latest big pharma company to collaborate on the development of novel inhibitors of KRAS, cellular signaling proteins which when mutated have been widely linked to the development of cancer but previously found difficult to design drugs against.

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