Gilead Hopes Selectivity Will Ease Safety Labeling For Filgotinib

On pace to file selective JAK1 inhibitor filgotinib for US approval in RA by year’s end, Gilead says the drug’s safety profile may allow for a labeling advantage compared with other drugs in the class.

Close Up Of Senior Man At Home Suffering With Arthritis - Image
Rheumatoid arthritis may be the first of several indications for filgotinib

As it nears the filing of a new drug application in the US for filgotinib in rheumatoid arthritis, Gilead Sciences Inc. is telling investors that it believes the selective JAK1 inhibitor may enjoy a better safety profile than other drugs in its class.

Gilead stepped in to partner on filgotinib with Galapagos NV back in 2015, making a $725m up-front commitment, after AbbVie Inc. opted not to license the compound earlier...

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