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With BMS Set To Join, What Next For CAR-T Market?

Outpatient Use Will Be Key

 
• By Andrew McConaghie

CAR-T therapies are groundbreaking in clinical terms, but have hit barriers in uptake. Can BMS’s challenger go one better than Yescarta and Kymriah?

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The chimeric antigen receptor T cell (CAR-T) therapies are among the most innovative to hit the market in recent years, but pioneers Novartis AG’s Kymriah and Gilead Sciences Inc.’s Yescarta have struggled to meet revenue expectations so far.

On 13 February, Bristol-Myers Squibb Co. filed its contender JCAR017 (lisocabtagene maraleucel (“liso-cel”)) with the US Food and Drug Administration, which will challenge Yescarta and Kymriah in the third-line...

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