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Gilead Partnership With Arcus Brings PD-1, TIGIT Assets To Its IO Portfolio

 
• By Joseph Haas

The 10-year partnership brings Arcus up-front funding with ample earnout opportunities, while Gilead gets extensive opt-in rights and an equity stake it can increase – and potentially a wholly owned dual checkpoint combination.

Partners shaking hands . in city environment
Gilead, Arcus agreed to an expansive, long-term R&D partnership

Gilead Sciences Inc. and Arcus Biosciences Inc. unveiled a 10-year immuno-oncology R&D collaboration on 27 May that brings the larger firm significant pipeline option rights with substantial downstream earning potential for the smaller company. Analysts uniformly praised the deal from Gilead’s standpoint, both in terms of what it adds in IO and the flexibility it offers; Arcus investors, however, responded negatively to the news.

Recent speculation suggested Gilead might be looking to acquire Arcus and its pipeline and discovery engine focused on the adenosine axis and the tumor microenvironment, but as a 27 May...

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