Pfizer Oncology Pipeline Shows Pivot To Targeted Therapies

Pfizer Inc.'s oncology pipeline has undergone a significant transition in the last five years, moving away from what were at one time high-profile immuno-oncology assets toward new targeted therapies. The failure of immuno-oncology combinations to deliver paradigm-changing successes has led many cancer drug developers to reprioritize next-generation targeted therapies.

Pfizer showcased its oncology pipeline during an R&D overview on 15 September, highlighting a late-stage portfolio that includes only two immunotherapy opportunities, one a new indication for the PD-L1 inhibitor Bavencio (avelumab) in first-line metastatic non-small cell lung