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ESMO: Merck & Co Vibostolimab Data Are Another Validation Of TIGIT

Shows Promise Alone And In Keytruda Combo

 
• By Kevin Grogan

A number of anti-TIGIT drugs are jockeying for position to provide benefit as monotherapies and in combinations for non-small cell lung cancer and Merck's offering is looking to challenge Roche's tiragolumab for the lead.

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Merck And Roche Jostling For Position In TIGIT Race • Source: Shutterstock

Merck & Co., Inc. is hoping to be at the head of the TIGIT field, seen by many as the most promising class in the new wave of immuno-oncology products and currently led by Roche Holding AG's tiragolumab, and early stage data on its candidate, vibostolimab, while limited, look promising.

The drug giant presented two abstracts from a Phase Ib trial at the virtual European Society for Medical Oncology congress, evaluating vibostolimab as a monotherapy and in combination with Merck’s...

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