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AZ's Fasenra Gets Boost From Steroid-Sparing Data

Expansion Plans For Big-Selling Biologic

 
• By Kevin Grogan

The POTENTE trial demonstrated Fasenra’s impact in eliminating or reducing oral corticosteroid use for severe asthma patients, which should help AstraZeneca as it takes on GlaxoSmithKline’s rival IL-5 inhibitor, Nucala.

Sodertalje, Sweden - April 27, 2014: Three purple flags with the logo for Atrazeneca flying in the wind on top of the flagpoles against the blue sky.
Flying the flag for Fasenra • Source: Shutterstock

AstraZeneca PLC's efforts to increase market share in the highly competitive severe asthma space for Fasenra will be helped by data showing that the interleukin-5 inhibitor eliminated the need for maintenance oral corticosteroids (OCS) in a large percentage of patients.

The company has unveiled high-level results from the PONENTE Phase IIIb open-label trial which showed that Fasenra (benralizumab) helped 62% of the nearly 600 severe asthma patients in the study...

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