PureTech Health plc-backed Vor Biopharma Inc. said on 11 November that it has licensed a clinical-stage chimeric antigen receptor T-cell (CAR-T) therapy candidate that targets CD33 from the US National Cancer Institute, one of two licensing deals inked by NCI in the past month. The candidate, developed by NCI pediatric oncology researcher Terry Fry, is in Phase I/II study for relapsed/refractory acute myeloid leukemia in children and young adults.
No financial terms were disclosed for the transaction. Vor, which launched in 2016 with what it described as a novel approach to CAR-T therapy for cancer, has its lead program, the engineered hematopoietic stem cell (eHSC) candidate VOR33, in preclinical development for AML. (Also see "IP Commercializer PureTech Enters CAR-T With Vor BioPharma Start-Up" - Scrip, 12 May, 2016
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