Tech Transfer Roundup: MD Anderson Working To Unlock Promise Of Tumor-Infiltrating Lymphocytes

The center is partnering with Obsidian to make autologous TILs work better after being infused back into patients by using IL-15, which may be less toxic than the high-dose IL-2 currently used.

Tech Transfer

Tumor-infiltrating lymphocytes have long been regarded as a promising modality for treating solid tumor cancers with cell therapy, but an ongoing challenge in tapping that potential has been manufacturing. Addressing that, along with defining a regulatory path, will be the key barriers to bringing to market a technology that researchers know is effective at fighting solid tumors, University of Texas MD Anderson Cancer Center'sJason Bock told Scrip.

Vice president and head of biologics development and therapeutic discovery at MD Anderson, Bock said hardly anyone – even at the US Food and Drug Administration – doubts that autologous...

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