Poxel/Sumitomo's Novel Diabetes Therapy Imeglimin Nears Japan Market

A Phase III-Ready Partnering Opportunity For EU/US

Poxel’s potential first-in-class diabetes therapy, imeglimin, could be approved in Japan this year, and a new partner is being sought for the EU and US – events that would transform the outlook for the decade-old Merck Serono spin-out.    

mitochondria
Imeglimin Targets Mitochondria Dysfunction • Source: Shutterstock

The metabolic diseases company, Poxel SA, expects its novel antidiabetic, imeglimin, will be approved in Japan this year, through partner Sumitomo Dainippon Pharma Co., Ltd., and also believes the candidate is a Phase III-ready opportunity for a potential partner to develop for the US and EU. 

The product is available as the previous EU/US licensee Metavant Sciences Inc said in November 2020 it would not move the candidate forward citing strategic reasons not related to efficacy or side effects; the Roivant

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