Developing anticancer drugs that act as ICOS agonists has notable promise as a fruitful research strategy, but clinical trials with one of the leading investigational candidates with this mode of action, GlaxoSmithKline plce’s feladilimab, have been halted by the company, casting a shadow over the field.
The setback is a second blow to GSK’s ambitions to return to the cancer marketplace in recent times, after it...