Catching Up With Fate: Deal With CRISPR Brings Nkarta Up In NK Cell Race

Partnership Seen As Validating CD70 As Antigen Target

The partnership helps close the gap between Nkarta and Fate Therapeutics in terms of the breadth of their pipelines.

3D illustration of T cells attacking a cancer cell (CAR-T cell therapy) - Illustration
The deal between Nkarta and CRISPR includes CD70 plus an undetermined target • Source: Shutterstock

The development and commercialization partnership that Nkarta, Inc. announced with CRISPR Therapeutics AG could help make Nkarta a bigger player in the natural killer (NK) cell therapy space, and also gives further validation to CD70 as an antigen target in hematology-oncology.

South San Francisco, CA-based Nkarta and Zug, Switzerland-based CRISPR announced the deal on 6 May, which will focus on the CD70 tumor antigen target and an additional target that remains undetermined, along with plans to develop a combined NK- and T-cell therapy candidate

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