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CDK4/6 Market: Is A Shakeup Underway?

 
• By Jessica Merrill

Pfizer's Ibrance still dominates the category but sales slowed in the first quarter, while Novartis’s Kisqali and Lilly's Verzenio both grew double digits.

Shaker
The CDK4/6 market may finally be undergoing a shakeup • Source: Alamy

Pfizer Inc.'s Ibrance (palbociclib) has dominated the CDK4/6 inhibitor category since it launched in 2015 for hormone receptor-positive (HR+), human epidermal growth factor receptor 2-negative (HER2-) advanced or metastatic breast cancer, despite the entry of two competitors. But now it appears Ibrance's momentum may be reaching a plateau.

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