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Byondis Seeks Partner For Lead ADC To Enter Crowded Breast Cancer Market

Positive Top-Line Results From TULIP Study

 
• By John Davis

Top-line results from the Phase III TULIP study show that Byondis’s next-generation antibody-drug conjugate, trastuzumab duocarmazine (SYD985) is superior to physicians' choice of therapy for delaying disease progression in patients with advanced HER2-positive breast cancer.

Guided Missiles
ADCs Are Often Likened To Guided Missiles • Source: Alamy

Netherlands-based Byondis B.V.’s lead candidate product, the next-generation antibody-drug conjugate, SYD985, has met its primary endpoint in the Phase III TULIP study in HER2-positive advanced breast cancer, and the company intends to explore partnering for the product, which it expects to submit for regulatory approval by the end of 2021. 

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