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KRAS Inhibitors Show Promise But Long Road Ahead, Say Experts

Tough Times For Cell Therapy

 
• By Vibha Ravi

Harvard Medical School’s Dr. Bruce Chabner, Bayer Pharma’s global head of research and Roivant Sciences founder, among others, share their views on the challenges and path ahead for KRAS inhibitors and other oncology modalities including CAR-T therapy.

Hand Holding Syringe Cancer Research In Background
KRAS Inhibitors Promising But A Way To Go • Source: Alamy

Kirsten rat sarcoma viral oncogene homolog (KRAS) inhibitors are emerging as an exciting cancer treatment option, with the recent US approval of Amgen, Inc.’s Lumakras (sotorasib) and breakthrough therapy designation for Mirati Therapeutics, Inc.’s adagrasib holding new hope for companies looking to develop KRAS-based oncology offerings.

Belonging to a group of proteins known as the RAS superfamily, the others being HRAS and NRAS, this genetic driver of several solid tumor types, including non-small cell lung cancer (NSCLC) and colorectal cancer was considered undruggable until recently

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Strong Showing For Bayer’s Pharma Business In Uncertain Times

 
• By Kevin Grogan

As CEO Anderson backs high prices for innovative drugs in Europe

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Join our China-based editors Dexter Yan and Xu Hu in this Chinese-language podcast looking at some of their recent interviews and other key coverage.

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